Hyaluronic Acid's Role in the Skin's Appearance

Hyaluronic acid plays an important role in the way your skin looks, feels, and functions. A natural complex sugar found in all mammals, it's a major component of the connective tissue matrix in the dermis—the dense, inner layer of skin beneath the epidermis. This matrix is made up of hyaluronic acid as well as two connective fibers—collagen and elastin.

By its nature, hyaluronic acid retains water like a sponge, absorbing more than 1,000 times its weight. This helps to attract and maintain water within the extracellular space, hydrating your skin and increasing its volume and density. Hyaluronic acid is also involved with the transport of essential nutrients to the skin's viable cells. Hyaluronic acid provides volume, helping to contribute to the skin's overall appearance.

As you age and your skin is exposed to environmental pollutants and the sun's ultraviolet rays, your cells gradually lose the ability to produce hyaluronic acid. Studies have shown that older skin typically has lower levels of hyaluronic acid than younger skin. As you age, your skin tissue becomes dehydrated and the collagen and elastin fibers lose their structure, resulting in a loss of skin volume and the formation of the facial wrinkles and folds that are common characteristics of aged skin.

Hyaluronic acid dermal fillers like Juvéderm® injectable gel can help to temporarily replace the lost hyaluronic acid and restore your skin's volume and smooth, natural appearance.

JUVÉDERM® is the ONLY hyaluronic acid (HA) filler FDA approved* to last up to 1 year

*Juvéderm® is indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).

Juvéderm® offers a high concentration of cross-linked hyaluronic acid for long-lasting results. In fact, it provides results that last up to 1 year!

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Important JUVÉDERM® Treatment Considerations

Juvéderm® Ultra and Juvéderm® Ultra Plus are indicated for injection into the mid to deep dermis for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds). Side effects were usually mild to moderate lasting 7 days or less and included temporary injection site reactions like redness, pain, firmness, swelling and bumps. For more information, please click on the “About Safety” link, or call the Allergan Product Support line at 1-877-345-5372.

BOTOX® Cosmetic is approved for the temporary treatment of moderate to severe frown lines between the brows in people ages 18-65.

Important Safety Information about BOTOX® Cosmetic

Serious heart problems and serious allergic reactions have been reported rarely. If you think you're having an allergic reaction or other reactions, such as difficulty swallowing, speaking or breathing, call your doctor immediately. The most common side effects following injection include temporary eyelid droop and nausea. Localized pain, infection, inflammation, tenderness, swelling, redness and/or bleeding/bruising may be associated with the injection. Patients with certain neuromuscular disorders such as ALS, myasthenia gravis or Lambert-Eaton syndrome may be at increased risk of serious side effects.

Click here for full BOTOX® Cosmetic prescribing information