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    • BOTOX® COSMETIC
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patient looks into the distance with a smile, her hands interlaced beneath her chin. patient looks into the distance with a smile, her hands interlaced beneath her chin.

ENHANCE.
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Actual patient treated with JUVÉDERM® VOLUMA® XC in the cheeks. Results may vary.

THE #1 CHOSEN
DERMAL FILLER COLLECTION*

*February 2022 provider survey data (N=938)

JUVÉDERM®ULTRA XC - Filler For Laugh Lines
JUVÉDERM® VOLUMA® XC - Filler For Cheek Enhancement
JUVÉDERM® VOLBELLA® XC - Filler For Lines Above The Lips

Patient looks into the camera with slight, knowing smile, with chin resting on folded hands.

Actual patient treated with JUVÉDERM® VOLUMA® XC in the cheeks and JUVÉDERM® Ultra XC in the lips. Results may vary.

LIFT. SMOOTH. PLUMP.

JUVÉDERM® is the leading collection of fillers. Each one adds volume and is designed for different needs in different areas of the face including lips, cheeks, or chin. How? It temporarily restores your skin's volume with a modified form of hyaluronic acid.

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JUVÉDERM® FILLERS FAQ

Find answers to the most commonly asked questions about the JUVÉDERM® Collection of Fillers.

JUVÉDERM® COLLECTION

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Expand text box Collapse text box What is JUVÉDERM®?

JUVÉDERM® is the #1 selling collection of hyaluronic acid fillers in the U.S. Each product in the JUVÉDERM® Collection of Fillers adds volume to a different area of the face—without surgery. All JUVÉDERM® fillers are smooth, crystal-clear gels that are administered by injection in your aesthetic healthcare provider's office.

Expand text box Collapse text box Where is JUVÉDERM® used?

Different formulations are approved to either volumize cheeks, smooth facial wrinkles and folds, smooth lines around the mouth, or plump the lips. The results are subtle and long-lasting.

JUVÉDERM® VOLLURE® XC softens moderate to severe facial wrinkles and folds by adding volume around the nose and mouth in adults over the age of 21.

JUVÉDERM® VOLUMA® XC injectable gel is for deep injection in the cheek area to correct age-related volume loss and for augmentation of the chin region to improve the chin profile in adults over 21.

JUVÉDERM® VOLBELLA® XC adds subtle volume to lips and softens the appearance of perioral lines.

JUVÉDERM® ULTRA PLUS XC smooths moderate to severe facial wrinkles and folds around your around your nose and mouth.

JUVÉDERM® ULTRA XC adds fullness and plumps lips as well as smooths and corrects moderate to severe wrinkles and folds in adults.

Expand text box Collapse text box Does JUVÉDERM® have FDA approval?

Products in the JUVÉDERM® Collection are FDA approved and have been widely studied. Numerous clinical studies have been completed globally evaluating the safety and effectiveness of Vycross® technology fillers. Please see below for more Important Safety Information.

Expand text box Collapse text box What is Vycross®? Is Vycross® the same as JUVÉDERM®?

Vycross® is the #1 chosen filler technology in the world. Vycross® is a proprietary technology designed by Allergan Aesthetics for use in its JUVÉDERM® collection of hyaluronic acid (HA) fillers, including JUVÉDERM® VOLUMA® XC, JUVÉDERM® VOLLURE® XC, and JUVÉDERM® VOLBELLA® XC. Vycross® technology cross-links HA molecules to create a smooth, and efficiently cross-linked filler. All Vycross® fillers contain a small quantity of lidocaine to decrease injection-site pain.

Expand text box Collapse text box What is hyaluronic acid?

The JUVÉDERM® Collection of Fillers is made from hyaluronic acid (HA). HA is a natural substance in the skin that delivers nutrients, helps the skin retain moisture and softness, and adds volume. Each product in the JUVÉDERM® Collection of Fillers is made from a modified form of HA.

Expand text box Collapse text box What is the treatment experience like?

Your aesthetic healthcare provider will take your medical history and provide a facial analysis. Be prepared to discuss your aesthetic areas of concern. This is not a surgical treatment. Actual treatment with JUVÉDERM® injectable gels can take 15 minutes to 60 minutes, depending on which area of your face is being treated.

Expand text box Collapse text box Does it hurt?

JUVÉDERM® injectable gels labeled with "XC" contain pain-reducing lidocaine to help manage pain or discomfort during the injection. You may also ask your aesthetic healthcare provider about a topical numbing cream or ice to help further minimize discomfort.

Expand text box Collapse text box What is the average treatment cost?

The cost not only includes the price of the product but, more importantly, the skill and expertise of the specialist or healthcare professional who is administering your treatment. Look for someone who is licensed and trained and has experience treating patients with the JUVÉDERM® Collection. Be wary of discount products or “cheap” JUVÉDERM® Collection treatments —if it sounds too good to be true, it probably is.

It is more important to find an experienced specialist who will take the time to understand your treatment goals and develop a treatment plan that is right for you.

Expand text box Collapse text box How can I save on treatments?

Join Allē, the new and improved loyalty program by the makers of JUVÉDERM®, for savings on treatments within the JUVÉDERM® Collection. With Allē, you can earn 200 points for qualifying JUVÉDERM® treatments that you can redeem for savings on future treatments.

Allē also rewards you for getting a variety of in-office treatments from other brands too. Then, redeem points for savings on your favorite Allergan Aesthetics brands. Use points as you go, or store them in your Wallet for big savings later. 100 Points = $10 toward qualifying products and treatments.

Expand text box Collapse text box When will I see results?

You will see results immediately/instantly.

Expand text box Collapse text box How long do results last?

Results may last one year to two years, with optimal treatment and depending on the formula used and the area treated. Please read each product description to see how long results last with each formula and treatment area, based on what was observed in clinical studies.

Expand text box Collapse text box Are there any reasons I shouldn’t receive JUVÉDERM® injectable gel fillers?

Do not receive JUVÉDERM® injectable gel fillers if you have a history of severe allergic reactions (anaphylaxis), or if you are allergic to lidocaine or the proteins (Gram-positive bacterial proteins) used to make hyaluronic acid (HA) in JUVÉDERM® injectable gel fillers.

Expand text box Collapse text box Do JUVÉDERM® fillers have an established safety profile?

JUVÉDERM® fillers have established safety profiles. The safety and effectiveness of JUVÉDERM® fillers have been evaluated in numerous clinical studies worldwide.

Expand text box Collapse text box Is treatment permanent?

Treatment with JUVÉDERM® fillers is not permanent. Depending on the JUVÉDERM® filler used and the treatment area, results may last one year to two years with optimal treatment.

Expand text box Collapse text box What are the common side effects?

The most common side effects are redness, swelling, pain, and tenderness. Minimize exercise, sun or heat exposure, and alcoholic beverages within the first 24 hours following treatment to avoid worsening these side effects. Talk to your licensed specialist about post-care instructions following treatment and please see below for more Important Safety Information.

Expand text box Collapse text box What is JUVÉDERM® VOLUMA® XC?

As you age, the cheeks may flatten and the skin may begin to sag. This is caused by natural loss of volume in the cheek area, or what the experts call age-related midface volume loss. JUVÉDERM® VOLUMA® XC is designed to add volume beneath the skin's surface, which provides lift and contour to the cheek area.

Expand text box Collapse text box How long does JUVÉDERM® VOLUMA® XC last?

JUVÉDERM® VOLUMA® XC provides natural-looking and long-lasting results that last up to 2 years with optimal treatment.

Expand text box Collapse text box What are the potential side effects of JUVÉDERM® VOLUMA® XC?

The most common side effects included temporary reactions at the treatment site such as tenderness, swelling, firmness, lumps/bumps, bruising, pain, redness, discoloration, and itching. Side effects were moderate (uncomfortable), and generally lasted 2 to 4 weeks. As with all skin injection procedures, there is a risk of infection.

Expand text box Collapse text box How does JUVÉDERM® VOLUMA® XC work?

As you age, the cheek area loses its youthful shape. The cheeks flatten out and the skin may begin to sag. JUVEDERM® VOLUMA® XC injectable gel is designed to temporarily reverse these signs of aging. It is a gel that is injected into the cheek area to lift the skin. It temporarily adds volume to the cheek area and results in a smoother contour and more youthful appearance to the face.

Expand text box Collapse text box What is JUVÉDERM® VOLUMA® XC?

JUVÉDERM® VOLUMA® XC injectable gel is designed for deep injection for augmentation of the chin region to improve the chin profile. Adding volume to the chin area creates shape and definition for adults over 21 years of age.

Expand text box Collapse text box How long does JUVÉDERM® VOLUMA® XC last?

JUVÉDERM® VOLUMA® XC provides results that can last up to 1 year in the chin with optimal treatment.

Expand text box Collapse text box What are the potential side effects of JUVÉDERM® VOLUMA® XC?

For chin augmentation, the most common side effects were temporary reactions at the treatment site, such as tenderness, firmness, swelling, pain, lumps/bumps, redness, itching and discoloration. Most of the side effects were mild in nature, and generally resolved in 2-4 weeks. As with all skin-injection procedures, there is a risk of infection.

Expand text box Collapse text box How does JUVÉDERM® VOLUMA® XC work?

JUVÉDERM® VOLUMA® XC is injected into the chin area to increase chin projection. It temporarily adds volume to the chin area and results in an improved chin shape. The addition of lidocaine helps to improve the comfort of the injection by reducing sensitivity to pain.

Expand text box Collapse text box What is JUVÉDERM® VOLLURE® XC?

JUVÉDERM® VOLLURE® XC is injected into the areas of facial tissue where moderate to severe facial wrinkles and folds occur, including the smile/laugh lines around the nose and mouth also known as nasolabial folds. JUVÉDERM® VOLLURE® XC is designed to temporarily correct facial wrinkles for a smoother appearance to the face for adults over the age of 21.

Expand text box Collapse text box How long does JUVÉDERM® VOLLURE® XC last?

The clinical study demonstrated JUVÉDERM® VOLLURE® XC lasts up to 18 months with optimal treatment.

Expand text box Collapse text box What are the potential side effects of JUVÉDERM® VOLLURE® XC?

The most common side effects included firmness, swelling, tenderness to touch, lumps/bumps, redness, pain, bruising, itching, and discoloration at the injection site. These side effects were usually mild or moderate in nature (causing little to some discomfort and impact on daily activities) and lasted 14 days or less.

Expand text box Collapse text box How does JUVÉDERM® VOLLURE® XC work?

Over time, wrinkles develop on your face, and nasolabial folds may become more visible. JUVÉDERM® VOLLURE® XC is designed to temporarily add volume to the facial wrinkles for a smoother appearance to the face. The lidocaine in the gel improves the comfort of the injection by reducing sensitivity to pain.

Expand text box Collapse text box What is JUVÉDERM® ULTRA PLUS XC?

First approved by the FDA in 2006, JUVÉDERM® ULTRA PLUS XC corrects moderate to severe facial wrinkles and folds, such as the parentheses lines or "smile/laugh lines" around the nose and mouth, also known as nasolabial folds. JUVÉDERM® ULTRA PLUS XC is injected into areas of facial tissue where moderate to severe facial wrinkles and folds occur to temporarily add volume to the skin, which may give the appearance of a smoother surface.

Expand text box Collapse text box How long does JUVÉDERM® ULTRA PLUS XC last?

JUVÉDERM® ULTRA PLUS XC lasts up to one year with optimal treatment.

Expand text box Collapse text box What are the potential side effects of JUVÉDERM® ULTRA PLUS XC?

The most commonly reported side effects of JUVÉDERM® ULTRA PLUS XC injectable gels were temporary injection-site redness, swelling, pain/tenderness, firmness, lumps/bumps, bruising, itching, and discoloration. They were predominantly mild or moderate in nature and lasted 7 days or less.

Expand text box Collapse text box How does JUVÉDERM® ULTRA PLUS XC work?

JUVÉDERM® ULTRA PLUS XC is injected into areas of facial tissue where moderate to severe facial wrinkles and folds occur to temporarily add volume to the skin, which may give the appearance of a smoother surface.

Expand text box Collapse text box What is JUVÉDERM® VOLBELLA® XC?

JUVÉDERM® VOLBELLA® XC injectable gel is for injection into the lips for lip augmentation and for correction of perioral lines (lines around the mouth), often called lipstick lines, vertical lip lines, or lip wrinkles, in adults over the age of 21.

Expand text box Collapse text box How long does JUVÉDERM® VOLBELLA® XC last?

JUVÉDERM® VOLBELLA® XC lasts up to 1 year, with optimal treatment.

Expand text box Collapse text box What are the potential side effects of JUVÉDERM® VOLBELLA® XC?

The most common side effects included temporary reactions at the treatment site such as tenderness, swelling, firmness, lumps/bumps, bruising, pain, redness, discoloration, and itching. Side effects were mild or moderate (uncomfortable) and generally lasted 30 days or less.

Expand text box Collapse text box How does JUVÉDERM® VOLBELLA® XC work?

JUVÉDERM® VOLBELLA® XC is a crystal-clear gel that is injected directly into and around the lips using an ultra-fine needle to temporarily plump the lips for lip augmentation and to smooth the appearance of lines around the mouth. The lidocaine gel improves the comfort of the injection by reducing sensitivity to pain.

Expand text box Collapse text box What is JUVÉDERM® Ultra XC?

JUVÉDERM® Ultra XC is an injectable gel that temporarily adds more fullness and plumps thin lips—whether your lips have thinned over time or you simply want fuller lips—in adults over the age of 21.

Expand text box Collapse text box How long does JUVÉDERM® Ultra XC treatment last?

JUVÉDERM® ULTRA XC lasts up to one year, with optimal treatment.

Expand text box Collapse text box What are the potential side effects of JUVÉDERM® Ultra XC?

For lip augmentation, most side effects were mild or moderate in nature with duration of 14 days or less. The most common side effects were temporary reactions at the treatment site such as tenderness, swelling, firmness, lumps/bumps, and bruising.

Expand text box Collapse text box How does JUVÉDERM® Ultra XC work?

JUVEDERM® Ultra XC is a crystal-clear gel that is injected directly into and around the lips using a small needle to temporarily add the desired range of fullness for lip enhancement in adults over the age of 21. The lidocaine in the gel improves the comfort of the injection by reducing sensitivity to pain.

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JUVÉDERM® Injectable Gel Fillers Important Information

APPROVED USES

JUVÉDERM® VOLUXTM XC injectable gel is for deep injection to improve moderate to severe loss of jawline definition in adults over the age of 21.

JUVÉDERM® VOLUMA® XC injectable gel is for deep injection in the cheek area to correct age-related volume loss and for augmentation of the chin region to improve the chin profile in adults over 21.

JUVÉDERM® VOLLURE® XC, JUVÉDERM® Ultra Plus XC, and JUVÉDERM® Ultra XC injectable gels are for injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds. JUVÉDERM® VOLLURE® XC injectable gel is for adults over 21.

JUVÉDERM® Ultra XC injectable gel is also for injection into the lips and perioral area for lip augmentation in adults over 21.

JUVÉDERM® VOLBELLA® XC injectable gel is for injection into the lips for lip augmentation and correction of perioral lines, and for injection into the undereye hollows to improve the appearance of undereye hollows in adults over the age of 21.

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JUVÉDERM® Injectable Gel Fillers Important Information

APPROVED USES

JUVÉDERM® VOLUXTM XC injectable gel is for deep injection to improve moderate to severe loss of jawline definition in adults over the age of 21.

JUVÉDERM® VOLUMA® XC injectable gel is for deep injection in the cheek area to correct age-related volume loss and for augmentation of the chin region to improve the chin profile in adults over 21.

JUVÉDERM® VOLLURE® XC, JUVÉDERM® Ultra Plus XC, and JUVÉDERM® Ultra XC injectable gels are for injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds. JUVÉDERM® VOLLURE® XC injectable gel is for adults over 21.

JUVÉDERM® Ultra XC injectable gel is also for injection into the lips and perioral area for lip augmentation in adults over 21.

JUVÉDERM® VOLBELLA® XC injectable gel is for injection into the lips for lip augmentation and correction of perioral lines, and for injection into the undereye hollows to improve the appearance of undereye hollows in adults over the age of 21.

IMPORTANT SAFETY INFORMATION

Are there any reasons why I should not receive any JUVÉDERM® formulation?

Do not use these products if you have a history of multiple severe allergies or severe allergic reactions (anaphylaxis), if you are allergic to lidocaine or the Gram-positive bacterial proteins used in these products, or if you have had previous allergic reactions to hyaluronic acid fillers.

What warnings should my doctor advise me about?

  • One of the risks with using dermal fillers is the unintentional injection into a blood vessel. The chances of this happening are very small, but if it does happen, the complications can be serious and may be permanent. These complications, which have been reported for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring of the skin. Most of these events are irreversible.

  • If you have changes in your vision, signs of a stroke (including sudden difficulty speaking, numbness or weakness in your face, arms or legs, difficulty walking, face drooping, severe headache, dizziness, or confusion), white appearance of the skin, or unusual pain during or shortly after treatment, you should notify your health care practitioner immediately.

  • The use of dermal fillers where skin sores, pimples, rashes, hives, cysts, or infections are present should be postponed, as this may delay healing or make skin problems worse

  • The effectiveness of removal of any dermal filler has not been studied.

What precautions should my doctor advise me about?

  • JUVÉDERM® VOLBELLA® XC should only be injected into undereye hollows by doctors who have completed the necessary training for this treatment area. To find a doctor, visit Juvederm.com/find-a-specialist. Doctors who complete the training will be listed with a symbol

  • The safety of these products for use during pregnancy or while breastfeeding has not been studied

  • The safety of JUVÉDERM® VOLUMA® XC has not been studied in patients under 35 years or over 65 years for cheek augmentation, or under 22 years and over 80 years for chin augmentation. The safety of JUVÉDERM® VOLUX™ XC, JUVÉDERM® VOLLURE® XC and JUVÉDERM® VOLBELLA® XC has not been studied in patients under 22 years, and the safety of JUVÉDERM® Ultra Plus XC and JUVÉDERM® Ultra XC has not been studied in patients under 18 years

  • The safety and effectiveness of treatment with JUVÉDERM® products in anatomical regions outside of their approved uses have not been established in clinical studies

  • If you have a history of excessive scarring (thick, hard scars) or pigmentation disorders, treatment in these patients has not been studied and may result in additional scars or changes in pigmentation

  • If you are planning other procedures including laser treatments or a chemical peel, there is a possible risk of inflammation at the treatment site if these procedures are performed closely before or after JUVÉDERM® injectable gel treatment

  • Tell your doctor if you are on therapy used to reduce your body’s natural defense system (such as steroids, chemotherapy, and medicines to treat autoimmune diseases, HIV, and AIDs), as these may increase your risk of infection; and medications that can prolong bleeding (such as aspirin, ibuprofen, or other blood thinners), as these may result in increased bruising or bleeding at the injection site.

  • Avoid applying makeup for 12 hours after treatment and minimize strenuous exercise, exposure to extensive sun or heat, and alcoholic beverages within the first 24 hours following treatment, as these may cause temporary redness, swelling, and/or itching at the injection site

  • JUVÉDERM® VOLUMA® XC was not studied in patients with significant loose skin of the chin, neck, or jaw

  • The effect of JUVÉDERM® VOLUMA® XC injection into the chin on facial hair growth has not been studied

  • Patients who experience skin injury near the site of JUVÉDERM® VOLUMA® XC injection may be at a higher risk for adverse events

  • Tell your doctor if you have already been injected with dermal fillers in the same area as the one(s) you are about to be treated for. This information helps your doctor decide when and whether you should get treatment

What are possible side effects of treatment?

The most commonly reported side effects with JUVÉDERM® injectable gels were redness, swelling, pain, tenderness, firmness, lumps/bumps, bruising, discoloration, and itching. For JUVÉDERM® VOLBELLA® XC, dryness was also reported.

These side effects are consistent with other facial injection procedures and most will resolve within 30 days. Your doctor may choose to treat side effects persisting longer with antibiotics, steroids, or hyaluronidase (an enzyme that breaks down hyaluronic acid).

As with all skin injection procedures, there is a risk of infection.

To report a side effect with any product in the JUVÉDERM® Collection, please call the Allergan® Product Support Department at 1-877-345-5372. Please also visit Juvederm.com or talk to your doctor for more information.

Products in the JUVÉDERM® Collection are available only by a licensed physician or properly licensed practitioner.

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© 2022 AbbVie. All rights reserved. JUVÉDERM® and its design are trademarks of Allergan Holdings France SAS, an AbbVie company, or its affiliates. Allē® and its design are service marks of Allergan, Inc., an AbbVie company. Allergan, Inc., an AbbVie company. All other trademarks are the property of their respective owners. JUV157402 08/22